Determining Utility System Value of Demand Flexibility From Grid-interactive Efficient Buildings

This report focuses on ways current methods and practices that establish the value to electric utility systems of distributed energy resource (DER) investments can be enhanced to determine the value of demand flexibility in grid-interactive efficient buildings that can provide grid services. The report introduces key valuation concepts that are applicable to demand flexibility that these buildings can provide and links to other documents that describe these concepts and their implementation in more detail.The scope of this report is limited to the valuation of economic benefits to the utility system. These are the foundational values on which other benefits (and costs) can be built. Establishing the economic value to the grid of demand flexibility provides the information needed to design programs, market rules, and rates that align the economic interest of utility customers with building owners and occupants. By nature, DERs directly impact customers and provide societal benefits external to the utility system. Jurisdictions can use utility system benefits and costs as the foundation of their economic analysis but align their primary cost-effectiveness metric with all applicable policy objectives, which may include customer and societal (non-utility system) impacts.This report suggests enhancements to current methods and practices that state and local policymakers, public utility commissions, state energy offices, utilities, state utility consumer representatives, and other stakeholders might support. These enhancements can improve the consistency and robustness of economic valuation of demand flexibility for grid services. The report concludes with a discussion of considerations for prioritizing implementation of these improvements

Cost of saving natural gas through efficiency programs funded by utility customers: 2012–2017

This study estimates the cost of saving a therm of natural gas from energy efficiency programs funded by utility customers during the period 2012 to 2017. Berkeley Lab researchers compiled and analyzed efficiency program data reported by investor-owned utilities and other program administrators in a dozen states representative of the four U.S. Census regions — Arkansas, California, Connecticut, Iowa, Massachusetts, Michigan, Minnesota, New Jersey, New York, Oklahoma, Rhode Island and Utah. Depending on the year, the dataset accounts for about 50 percent to 70 percent of annual national spending on natural gas efficiency programs. The estimated cost of saving natural gas during the study period is $0.40 per therm. The analysis also includes estimates of the program administrator cost of saved energy for three core sectors for natural gas: commercial and industrial, residential, and low-income households. It aggregates these sectors to provide regional and national values. Our metrics include savings-weighted averages, unweighted medians, and interquartile ranges (25th and 75th percentiles) of the levelized program administrator cost of saving gas, in constant 2017 dollars. In addition, the study analyzes cost trends during the study period, finding that average program costs trended downward. The U.S. Department of Energy’s Building Technologies Office supported this work

Definition, reporting, and interpretation of composite outcomes in clinical trials: systematic review

Objective To study how composite outcomes, which have combined several components into a single measure, are defined, reported, and interpreted

Cost of Saving Electricity Through Efficiency Programs Funded by Customers of Publicly Owned Utilities: 2012–2017

This report finds that energy efficiency programs for customers of publicly owned utilities saved electricity at an average cost of 2.4 cents per kilowatt-hour (kWh) from 2012 to 2017. Utilities use such cost performance metrics to assess effectiveness of efficiency program portfolios, determine what programs to offer customers, and, more broadly, ensure electricity system reliability at the most affordable cost as part of electric utility resource adequacy planning and resource procurement processes. The study analyzed efficiency program data reported by 111 program administrators for 219 publicly owned utilities in 14 states — about 90 percent of the municipal utilities and public utility districts that report the data to the Energy Information Administration (EIA). The data represent 88 percent of all spending and 75 percent of all savings that publicly owned utilities reported to EIA in those years. Berkeley Lab used data from several sources, including data provided directly by American Public Power Association members, publicly available annual reports and regional data collections

Dynamical compactification from de Sitter space

We show that D-dimensional de Sitter space is unstable to the nucleation of non-singular geometries containing spacetime regions with different numbers of macroscopic dimensions, leading to a dynamical mechanism of compactification. These and other solutions to Einstein gravity with flux and a cosmological constant are constructed by performing a dimensional reduction under the assumption of q-dimensional spherical symmetry in the full D-dimensional geometry. In addition to the familiar black holes, black branes, and compactification solutions we identify a number of new geometries, some of which are completely non-singular. The dynamical compactification mechanism populates lower-dimensional vacua very differently from false vacuum eternal inflation, which occurs entirely within the context of four-dimensions. We outline the phenomenology of the nucleation rates, finding that the dimensionality of the vacuum plays a key role and that among vacua of the same dimensionality, the rate is highest for smaller values of the cosmological constant. We consider the cosmological constant problem and propose a novel model of slow-roll inflation that is triggered by the compactification process.Comment: Revtex. 41 pages with 24 embedded figures. Minor corrections and added reference

RNA-Seq identifies genes whose proteins are upregulated during syncytia development in murine C2C12 myoblasts and human BeWo trophoblasts

The fusion of villous cytotrophoblasts into the multinucleated syncytiotrophoblast is critical for the essential functions of the mammalian placenta. Using RNA-Seq gene expression, quantitative protein expression, and siRNA knockdown we identified genes and their cognate proteins which are similarly upregulated in two cellular models of mammalian syncytia development (human BeWo cytotrophoblast to syncytiotrophoblast and murine C2C12 myoblast to myotube). These include DYSF, PDE4DIP, SPIRE2, NDRG1, PLEC, GPR146, HSPB8, DHCR7, and HDAC5. These findings provide avenues for further understanding of the mechanisms underlying mammalian placental syncytiotrophoblast development

Development of a Stable Virus-Like Particle Vaccine Formulation against Chikungunya Virus and Investigation of the Effects of Polyanions

Chikungunya virus (CHIKV) is an alphavirus that infects millions of people every year, especially in the developing world. The selective expression of recombinant CHIKV capsid and envelope proteins results in the formation of self-assembled virus-like particles (VLPs) that have been shown to protect nonhuman primates against infection from multiple strains of CHIKV. This study describes the characterization, excipient screening, and optimization of CHIKV VLP solution conditions towards the development of a stable parenteral formulation. The CHIKV VLPs were found to be poorly soluble at pH 6 and below. Circular dichroism, intrinsic fluorescence, and static and dynamic light scattering measurements were therefore performed at neutral pH, and results consistent with the formation of molten globule structures were observed at elevated temperatures. A library of GRAS excipients was screened for their ability to physically stabilize CHIKV VLPs using a high-throughput turbidity based assay. Sugars, sugar alcohols, and polyanions were identified as potential stabilizers and the concentrations and combinations of select excipients were optimized. The effects of polyanions were further studied, and while all polyanions tested stabilized CHIKV VLPs against aggregation, the effects of polyanions on conformational stability varied

Detection of a Westward Hotspot Offset in the Atmosphere of a Hot Gas Giant CoRoT-2b

Short-period planets exhibit day-night temperature contrasts of hundreds to thousands of degrees K. They also exhibit eastward hotspot offsets whereby the hottest region on the planet is east of the substellar point; this has been widely interpreted as advection of heat due to eastward winds. We present thermal phase observations of the hot Jupiter CoRoT-2b obtained with the IRAC instrument on the Spitzer Space Telescope. These measurements show the most robust detection to date of a westward hotspot offset of 23 $\pm$ 4 degrees, in contrast with the nine other planets with equivalent measurements. The peculiar infrared flux map of CoRoT-2b may result from westward winds due to non-synchronous rotation magnetic effects, or partial cloud coverage, that obscures the emergent flux from the planet's eastern hemisphere. Non-synchronous rotation and magnetic effects may also explain the planet's anomalously large radius. On the other hand, partial cloud coverage could explain the featureless dayside emission spectrum of the planet. If CoRoT-2b is not tidally locked, then it means that our understanding of star-planet tidal interaction is incomplete. If the westward offset is due to magnetic effects, our result represents an opportunity to study an exoplanet's magnetic field. If it has Eastern clouds, then it means that our understanding of large-scale circulation on tidally locked planets is incomplete.Comment: 30 pages, 4 figures, 15 supplementary figure